If you are allergic to clozapine, you should not take Clozaril. Common allergic reactions include the sudden appearance of hives and the swelling of the lips, face, tongue, or throat. Be sure to mention to your doctor if you have had any serious reactions to similar medications.
Clozaril is not recommended for use by older adults with dementia or dementia-related issues as it may increase the risk of death. If you have or have ever had heart disease, heart failure, irregular heartbeat, stroke, liver disease, kidney disease, diabetes, glaucoma or seizures, you should talk to your doctor before you take this drug. Tell your doctor if you have ever had urinary issues or problems with your prostate.
Let your doctor know if you have phenylketonuria. Orally disintegrating Clozaril tablets contain aspartame, which forms phenylalanine.
Clozaril may interact with other medications or supplements, including antihistamines, antidepressants, antibiotics, antifungal drugs, vitamins, minerals, herbal products, sleeping pills, HIV medications, high blood pressure medications, and more. If you are taking other prescription drugs or supplements, you should check with your doctor or pharmacist before taking this medication.
A single tablet of Clozaril may be extremely toxic to toddlers. Confusion, involuntary muscle movement, nerve damage, coma, and respiratory arrest may occur if toddlers ingest just 50-200 mg of clozapine.