This medication may cause suicidal thoughts or behavior in children, teenagers, and young adults (aged 24 or younger), particularly during the first few months of treatment. These thoughts and actions may return if the dosage is changed. Call your doctor immediately if you detect any drastic changes in mood or develop behaviors that cause you to worry.
Using this medication over a long period of time may cause serotonin syndrome or neuroleptic malignant syndrome. These conditions may be fatal. Symptoms associated with these conditions include twitching muscles, problems with coordination, fast heartbeat, high or low blood pressure, hallucinations, changes in mental state, and loss of consciousness.
Do not take this medication within two weeks of taking a monoamine oxidase inhibitor (MAOI) as serious and possibly fatal drug interactions may occur. Do not take an MAOI drug until at least two weeks after you stop taking this medication.
If you have or have ever had heart disease, heart failure, glaucoma, stomach or esophagus bleeding, or liver or kidney disease, you should talk to your doctor before you take Paxil. You should also mention any severe reactions you may have had to similar medications. Tell your doctor if you currently have or have had any issues with addictive drugs, including street drugs or prescription medication.
This medication may cause serious complications in newborns if taken during pregnancy or while breastfeeding. In 2005, the United States Food and Drug Administration reported that Paxil may cause heart malformations in newborns if taken by pregnant women. If you become pregnant while taking this medication, you should discuss possible alternative treatments for your condition with your doctor.
Paxil may interact with other medications or supplements, including antihistamines, anticoagulants, antidepressants, antifungal medications, sleeping pills, pain relievers, high blood pressure medications, minerals, vitamins, and certain herbs such as St. John’s wort. If you are currently taking other prescription drugs or supplements, you should check with your doctor or pharmacist before taking this drug.