This medication may lead to or increase suicidal thoughts and actions in young adults (aged 24 or younger), teenagers, and children—especially at the start of treatment or if the dosage is altered. In addition to acts and thoughts of suicide, one study suggests that this drug may increase self-harm, aggression, and violence in children and adolescents. Pay attention to new or sudden changes in mood, thoughts, or behavior. Contact your health care provider if any changes appear severe, or if they concern you.
People who use this drug may develop a potentially life-threatening condition called serotonin syndrome. This condition is characterized by high or low blood pressure, racing heartbeat, muscle stiffness, muscle twitching, dizziness, diarrhea, nausea, vomiting, tremors, seizures, and loss of consciousness.
If you have ever had a heart attack, a history of heart disease, diabetes, glaucoma, or liver disease, talk to your health care provider before you take Prozac. Talk to your doctor about any electroshock therapy you are receiving or have received prior to beginning this medication. Adults over the age of 65 may experience severe side effects; if you are in this age group, work with your doctor to find an alternative treatment for your condition.
It is possible for this drug to interact with other medications or supplements, including antihistamines, anticoagulants, other antidepressants, antifungals, medication for sleep issues, herbal supplements, pain relief medication, blood pressure drugs, migraine medications, vitamins, minerals, and more. If you are taking any prescription drugs or regularly taking supplements, ask your doctor about any possible interactions before taking Prozac.