Teenagers and young adults may experience an increase in suicidal thoughts and actions, particularly during the first few months of treatment. Similar effects may be experienced when the dose is adjusted.
Long-term use of this medication has been linked with a severe and potentially fatal condition called serotonin syndrome. Symptoms of this condition include muscle twitching, muscle rigidity, fast heartbeat, excessive sweating or fever, nausea, vomiting, diarrhea, drastic changes in mood, agitation, hallucinations, and loss of consciousness.
Before taking any psychotropic medication, including Zoloft, it is important to discuss your complete health history and medication use with your doctor. You should also mention any serious reactions you may have had to other similar medications. If you drink alcohol on a regular basis, talk to your doctor about interactions this drug may have as a result of your alcohol use.
Zoloft may interact with other medications or supplements, including but not limited to:
- Antabuse (disulfiram)
- Medications for sleep issues
- Natural herbs, especially St. John’s wort
- Medications for pain relief
- Medication for issues with blood pressure
- Migraine medications
If you are taking any prescription drugs or regularly taking supplements, consult with your physician before beginning treatment with this drug.